Are they safe to use?

Application of capsaicin creams can make your skin burn or sting, but this discomfort generally lessens within a few weeks of daily use. Wash your hands thoroughly after each application and avoid touching your eyes and mucous membranes. You may need to wear latex gloves when applying the cream.

If you are allergic to aspirin or are taking blood thinners, check with your doctor before using topical medications that contain salicylates. Also, using too much can be toxic.

Don't use topical pain relievers on broken or irritated skin or with a heating pad or bandage.